Biological Safety Cabinets and Their Classifications

An important piece of safety equipment will be the Biological Safety Cabinet (BSCs) in which manipulations of infectious microorganisms are performed. Biological safety cabinets will be the primary suggests of containment developed for working safely with infectious microorganisms. Horizontal clean benches that direct towards the operator will not be biological safety cabinets and need to not be used for handling infectious, toxic or sensitizing materials. BSCs are created to provide each a clean work atmosphere and protection for employees who work with biological hazards thus biosafety cabinet's uses vertical laminar airflow to create a barrier to airborne particles, for example microorganisms as vertical laminar air flow delivers protection for both the personnel and the product. Get far more details about


Biosafety cabinets use the HEPA filtered air for the recirculation over the work area. The HEPA filter removes airborne particles in the air, but will not eliminate chemical fumes; for that reason Biosafety cabinets should not be confused using the fume hood. Biosafety cabinets usually are not the Fume Hood. Biosafety cabinets are equipped with Ultraviolet lamp that supplies protection against contamination, but because the UV light can not penetrate the dust particles, for that reason an additional chemical disinfectant, iodophor really should be use for the cleaning and decontaminating the work region.


Use of biosafety cabinets is recommended for the manipulations of pathogens or antineoplastics which can make aerosols and for all of the airborne transmitted pathogens (like Brucella abortus, Mycobacterium tuberculosis, and so on).


There are actually 3 classes of biological safety cabinets;


BSCs Class I: an open-front damaging pressure cabinet. The exhaust air in the cabinet is filtered by a HEPA filter. This class offers personnel and environmental protection, but not product protection.


BSCs Class II: is definitely an open-front, ventilated cabinet. This cabinet provides a HEPA-filtered, recirculated mass airflow within the work space. The exhaust air in the cabinet can also be filtered by HEPA filters. This class provides personnel, atmosphere and product protection.


BSCs Class III: is a completely enclosed ventilated cabinet of gas-tight construction. Operations within the Class III cabinet are conducted by way of attached rubber gloves. When in use, the Class III cabinet is maintained by means of adverse air pressure of no less than 0.5 inches water gauge. Supply air is drawn in to the cabinet through HEPA filters. The cabinet exhaust air is filtered by two HEPA filters, installed in series, prior to discharge outdoors of the facility. The exhaust fan for the Class III cabinet is typically separate in the exhaust fans of the facility's ventilation system.

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